Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00133)
Xenobiotics Name
Capecitabine
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
60953
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Dihydrothymine dehydrogenase (DPYD) DME Info Homo sapiens [2]
References
1 Effects of capecitabine and vinorelbine on cell proliferation, metabolism and COX2 and p16 expression in breast cancer cell lines and solid tumour tissues. Biomed Pharmacother. 2007 Oct;61(9):596-600.
2 DPD is a molecular determinant of capecitabine efficacy in colorectal cancer. Int J Oncol. 2007 Aug;31(2):413-8.

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