Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00144)
Xenobiotics Name
Bexarotene
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
82146
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Asparagine synthetase (ASNS) DME Info Homo sapiens [1]
Transglutaminase K (TGM1) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Aldo-keto reductase 1C1 (AKR1C1) DME Info Homo sapiens [1]
Aldo-keto reductase 1C3 (AKR1C3) DME Info Homo sapiens [1]
Retinoic acid 4-hydroxylase 26A1 (CYP26A1) DME Info Homo sapiens [1]
Short-chain dehydrogenase/reductase retSDR1 (DHRS3) DME Info Homo sapiens [1]
Transglutaminase H (TGM2) DME Info Homo sapiens [1]
References
1 Identification of biomarkers modulated by the rexinoid LGD1069 (bexarotene) in human breast cells using oligonucleotide arrays. Cancer Res. 2006 Dec 15;66(24):12009-18.
2 Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells. Cell Growth Differ. 1996 Aug;7(8):997-1004.

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