General Information of Xenobiotics (ID: XEO00151)
Xenobiotics Name
Imatinib mesylate
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
123596
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aldehyde dehydrogenase 2 (ALDH2) DME Info Homo sapiens [1]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [2]
References
1 A systems biology understanding of the synergistic effects of arsenic sulfide and Imatinib in BCR/ABL-associated leukemia. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3378-83.
2 Anti-leukemic effects of gallic acid on human leukemia K562 cells: downregulation of COX-2, inhibition of BCR/ABL kinase and NF-B inactivation. Toxicol In Vitro. 2012 Apr;26(3):396-405.

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