General Information of Xenobiotics (ID: XEO00207)
Xenobiotics Name
Oxaliplatin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
133611933
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Adenosine aminohydrolase (ADA) DME Info Homo sapiens [1]
Asparagine synthetase (ASNS) DME Info Homo sapiens [2]
Catalase (CAT) DME Info Homo sapiens [3]
Metallothionein-2A (MT2A) DME Info Homo sapiens [4]
Thymidylate synthase (TYMS) DME Info Homo sapiens [5]
DME(s) Induced by This Xenobiotics
Glutathione S-transferase pi (GSTP1) DME Info Homo sapiens [1]
Putrescine acetyltransferase (SSAT1) DME Info Homo sapiens [6]
References
1 Gastrodin ameliorates oxidative stress and proinflammatory response in nonalcoholic fatty liver disease through the AMPK/Nrf2 pathway. Phytother Res. 2016 Mar;30(3):402-11.
2 Combining computational and biochemical studies for a rationale on the anti-aromatase activity of natural polyphenols. ChemMedChem. 2007 Dec;2(12):1750-62.
3 High-fat feeding reduces endothelium-dependent vasodilation in rats: differential mechanisms for saturated and unsaturated fatty acids? Clin Exp Pharmacol Physiol. 2006 Aug;33(8):708-13.
4 Preferential inhibition of paraoxonase activity of human paraoxonase 1 by negatively charged lipids. J Lipid Res. 2004 Dec;45(12):2211-20.
5 High-affinity binding of fatty acyl-CoAs and peroxisome proliferator-CoA esters to glutathione S-transferases effect on enzymatic activity. Eur J Biochem. 1999 Nov;266(1):143-50.
6 Effects of oleamide on choline acetyltransferase and cognitive activities. Biosci Biotechnol Biochem. 2003 Jun;67(6):1284-91.

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