Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00211)
Xenobiotics Name
Pemetrexed
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
135410875
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Thymidylate synthase (TYMS) DME Info Homo sapiens [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Thymidylate synthase (TYMS) DME Info IC50 = 11 microM [1]
References
1 Design, Synthesis, and Biological Activities of Classical N-[4-[2-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic Acid and Its 6-methyl Derivative as Potential Dual Inhibitors of Thymidylate Synthase and Dihydrofolate Reductase and as Potential Antitumor Agents J Med Chem. 2003 Feb 13;46(4):591-600.

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