General Information of Xenobiotics (ID: XEO00229)
Xenobiotics Name
Temsirolimus
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
148191
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Dihydrothymine dehydrogenase (DPYD) DME Info Homo sapiens [1]
Thymidylate synthase (TYMS) DME Info Homo sapiens [2], [3]
References
1 Pyridoxal oxime derivative potency to reactivate cholinesterases inhibited by organophosphorus compounds. Toxicol Lett. 2016 Nov 16;262:114-122.
2 Centrally acting oximes in reactivation of tabun-phosphoramidated AChE. Chem Biol Interact. 2013 Mar 25;203(1):77-80.
3 Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates. Chem Biol Interact. 2013 Mar 25;203(1):67-71.

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