Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00270)
Xenobiotics Name
Auranofin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
6333901
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Thioredoxin reductase TR1 (TXNRD1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cellular glutathione peroxidase (GPX1) DME Info Homo sapiens [2]
References
1 Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors. Free Radic Biol Med. 2011 Mar 15;50(6):689-99.
2 Mitochondrial protection by the thioredoxin-2 and glutathione systems in an in vitro endothelial model of sepsis. Biochem J. 2011 May 15;436(1):123-32.

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