Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00290)
Xenobiotics Name
Dopamine hydrochloride
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
65340
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 2D6 (CYP2D6) DME Info Homo sapiens [1]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [1]
Glutathione S-transferase alpha-1 (GSTA1) DME Info Homo sapiens [2]
Glutathione S-transferase mu-1 (GSTM1) DME Info Homo sapiens [2]
Glutathione S-transferase pi (GSTP1) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Vitamin B12 methionine synthase (MTR) DME Info Homo sapiens [3]
References
1 Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening. Drug Metab Dispos. 2008 Jul;36(7):1322-31.
2 Inhibition of human glutathione S-transferases by dopamine, alpha-methyldopa and their 5-S-glutathionyl conjugates. Chem Biol Interact. 1994 Jan;90(1):87-99.
3 Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal. Mol Psychiatry. 2004 Apr;9(4):358-70.

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