Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00298)
Xenobiotics Name
Galantamine hydrobromide
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
121587
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Acetylcholinesterase (ACHE) DME Info Homo sapiens [1]
Butyrylcholine esterase (BCHE) DME Info Homo sapiens [2]
Carboxylesterase 2 (CES2) DME Info Homo sapiens [3]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Acetylcholinesterase (ACHE) DME Info IC50 = 0.1 microM [1]
Butyrylcholine esterase (BCHE) DME Info IC50 = 0.17 microM [2]
References
1 Design and synthesis of N-substituted-2-hydroxyiminoacetamides and interactions with cholinesterases. Chem Biol Interact. 2016 Nov 25;259(Pt B):122-132.
2 Lichens of parmelioid clade as promising multitarget neuroprotective agents. Chem Res Toxicol. 2019 Jun 17;32(6):1165-1177.
3 Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors. Chem Biol Interact. 2013 Mar 25;203(1):226-30.

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