Detail Information of Xenobiotics
General Information of Xenobiotics (ID: XEO00304) | ||||||
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Xenobiotics Name |
Lapatinib ditosylate
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Xenobiotics Type |
Pharmaceutical Agent(s)
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Classification |
Approved/Marketed Drug
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Structure |
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3D MOL | 2D MOL | |||||
PubChem CID | ||||||
DME(s) Modulated by This Xenobiotics | ||||||
DME(s) Induced by This Xenobiotics | ||||||
Quinone reductase 1 (NQO1) | DME Info | Homo sapiens | [1] | |||
References | ||||||
1 | P450 3A-catalyzed O-dealkylation of lapatinib induces mitochondrial stress and activates Nrf2. Chem Res Toxicol. 2016 May 16;29(5):784-96. |
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