Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00321)
Xenobiotics Name
Rivastigmine tartrate
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
6918078
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Butyrylcholine esterase (BCHE) DME Info Homo sapiens [1]
Carboxylesterase 2 (CES2) DME Info Homo sapiens [2]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [3]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Butyrylcholine esterase (BCHE) DME Info IC50 = 0.03 microM [1]
References
1 Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor. J Med Chem. 2014 Oct 9;57(19):8167-79.
2 In vitro inhibition of human cGMP-specific phosphodiesterase-5 by polyphenols from red grapes. J Agric Food Chem. 2005 Mar 23;53(6):1960-5.
3 Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity. Eur J Biochem. 1999 Oct 1;265(1):27-34.

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