Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00351)
Xenobiotics Name
Daunorubicin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
30323
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Quinone reductase 1 (NQO1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cellular glutathione peroxidase (GPX1) DME Info Homo sapiens [2], [3]
References
1 High-throughput library screening identifies two novel NQO1 inducers in human lung cells. Am J Respir Cell Mol Biol. 2012 Mar;46(3):365-71.
2 Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment. Arch Toxicol. 2016 Nov;90(11):2763-2777.
3 Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes. Arch Toxicol. 2018 Jan;92(1):371-381.

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