Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00377)
Xenobiotics Name
Pravastatin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
54687
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
HMG-CoA reductase (HMGCR) DME Info Homo sapiens [1], [2]
DME(s) Induced by This Xenobiotics
Catalase (CAT) DME Info Homo sapiens [3]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data HMG-CoA reductase (HMGCR) DME Info IC50 = 0.005591 microM [1], [2]
References
1 A transcriptomic analysis of black cohosh: actein alters cholesterol biosynthesis pathways and synergizes with simvastatin. Food Chem Toxicol. 2018 Oct;120:356-366.
2 Currently available hypolipidaemic drugs and future therapeutic developments. Baillieres Clin Endocrinol Metab. 1995 Oct;9(4):825-47.
3 Gene expression changes in human lung cells exposed to arsenic, chromium, nickel or vanadium indicate the first steps in cancer. Metallomics. 2012 Aug;4(8):784-93.

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