Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00392)
Xenobiotics Name
Vincristine
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
5978
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Dipeptidyl peptidase IV (DPP4) DME Info Homo sapiens [1], [2]
Methionine-tRNA ligase mitochondrial (MARS2) DME Info Homo sapiens [1], [2]
Phosphoribosylformylglycinamidine synthase (PFAS) DME Info Homo sapiens [1], [2]
Phosphoglucomutase 1 (PGM1) DME Info Homo sapiens [1]
Selenocysteine lyase (SCLY) DME Info Homo sapiens [3]
DME(s) Induced by This Xenobiotics
Cytochrome P450 4F2 (CYP4F2) DME Info Homo sapiens [4]
Metallothionein-2A (MT2A) DME Info Homo sapiens [4]
Putrescine acetyltransferase (SSAT1) DME Info Homo sapiens [2]
References
1 Integrated 'omics analysis reveals new drug-induced mitochondrial perturbations in human hepatocytes. Toxicol Lett. 2018 Jun 1;289:1-13.
2 Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology. 2018 Jan 15;393:160-170.
3 Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach. Arch Toxicol. 2013 Jan;87(1):123-43.
4 Stem cell transcriptome responses and corresponding biomarkers that indicate the transition from adaptive responses to cytotoxicity. Chem Res Toxicol. 2017 Apr 17;30(4):905-922.

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