Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00420)
Xenobiotics Name
Pargyline
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
4688
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Monoamine oxidase type B (MAO-B) DME Info Homo sapiens [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Monoamine oxidase type B (MAO-B) DME Info IC50 = 0.13 microM [1], [2]
References
1 Structure-based design and optimization of multitarget-directed 2H-chromen-2-one derivatives as potent inhibitors of monoamine oxidase B and cholinesterases. J Med Chem. 2015 Jul 23;58(14):5561-78.
2 Nonpeptidic propargylamines as inhibitors of lysine specific demethylase 1 (LSD1) with cellular activity. J Med Chem. 2013 Sep 26;56(18):7334-42.

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