Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00445)
Xenobiotics Name
Vildagliptin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
6918537
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Dipeptidyl peptidase IV (DPP4) DME Info Homo sapiens [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Dipeptidyl peptidase IV (DPP4) DME Info IC50 = 0.00058 microM [1]
References
1 2-({6-[(3R)-3-amino-3-methylpiperidine-1-yl]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5H-pyrrolo[3,2-d]pyrimidine-5-yl}methyl)-4-fluorobenzonitrile (DSR-12727): a potent, orally active dipeptidyl peptidase IV inhibitor without mechanism-based inactivation of CYP3A. Bioorg Med Chem. 2011 Sep 15;19(18):5490-9.

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