General Information of Xenobiotics (ID: XEO00457)
Xenobiotics Name
Estriol
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
5756
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aromatase (CYP19A1) DME Info Homo sapiens [1]
Sulfotransferase 1E1 (SULT1E1) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Nitric oxide synthase endothelial (NOS3) DME Info Homo sapiens [3]
References
1 Aflatoxin B1--a potential endocrine disruptor--up-regulates CYP19A1 in JEG-3 cells. Toxicol Lett. 2011 May 10;202(3):161-7.
2 Development and validation of a fluorescence HPLC-based screening assay for inhibition of human estrogen sulfotransferase. Anal Biochem. 2006 Oct 1;357(1):85-92.
3 17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhibiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression. J Biol Chem. 2003 Apr 4;278(14):11746-52.

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