Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00515)
Xenobiotics Name
Benoxaprofen
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug Marketed but Withdrawn from Market
Structure
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3D MOL 2D MOL
PubChem CID
39941
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Arachidonate 5-lipoxygenase (ALOX5) DME Info Homo sapiens [1], [2]
References
1 In vitro inhibition of leukotriene B4 formation by exogeneous 5-lipoxygenase inhibitors is associated with enhanced generation of 15-hydroxy-eicosatetraenoic acid (15-HETE) by human neutrophils. Arch Dermatol Res. 1988;280(7):430-6.
2 Meclofenamate sodium is an inhibitor of both the 5-lipoxygenase and cyclooxygenase pathways of the arachidonic acid cascade in vitro. Prostaglandins Leukot Med. 1986 Aug;23(2-3):229-38.

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