Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00516)
Xenobiotics Name
Danthron
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug Marketed but Withdrawn from Market
Structure
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3D MOL 2D MOL
PubChem CID
2950
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Unclear metabolic mechanism (DME-unclear) DME Info Streptococcus mutans [1]
Glutamate racemase (MurI) DME Info Streptococcus mutans [1]
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [2]
References
1 In vitro inhibition of Streptococcus mutans biofilm formation on hydroxyapatite by subinhibitory concentrations of anthraquinones. Antimicrob Agents Chemother. 2007 Apr;51(4):1541-4.
2 Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways. Chem Res Toxicol. 2011 Jan 14;24(1):20-9.

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