Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00518)
Xenobiotics Name
Formestane
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug Marketed but Withdrawn from Market
Structure
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3D MOL 2D MOL
PubChem CID
11273
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aromatase (CYP19A1) DME Info Homo sapiens [1]
Estradiol 17-beta-dehydrogenase 1 (HSD17B1) DME Info Homo sapiens [2]
References
1 A comparison of two human cell lines and two rat gonadal cell primary cultures as in vitro screening tools for aromatase modulation. Toxicol In Vitro. 2012 Feb;26(1):107-18.
2 Mammalian lignans and genistein decrease the activities of aromatase and 17beta-hydroxysteroid dehydrogenase in MCF-7 cells. J Steroid Biochem Mol Biol. 2005 Apr;94(5):461-7.

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