Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00541)
Xenobiotics Name
Motexafin gadolinium
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 2 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
158385
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
L-glutamine amidohydrolase (GLS) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Succinate-semialdehyde dehydrogenase (ALDH5A1) DME Info Homo sapiens [2]
Glutathione reductase (GSR) DME Info Homo sapiens [1]
Metallothionein-2A (MT2A) DME Info Homo sapiens [2]
References
1 Monomethylarsonous acid inhibited endogenous cholesterol biosynthesis in human skin fibroblasts. Toxicol Appl Pharmacol. 2014 May 15;277(1):21-9.
2 Cytotoxicity and gene expression changes induced by inorganic and organic trivalent arsenicals in human cells. Toxicology. 2013 Oct 4;312:18-29.

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