Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00544)
Xenobiotics Name	Ebselen
Xenobiotics Type	Pharmaceutical Agent(s)
Classification	Drug in Phase 2 Clinical Trial
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=3194"></iframe>
Structure	3D MOL	2D MOL
PubChem CID	3194
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
	Arachidonate 5-lipoxygenase (ALOX5)	DME Info	Homo sapiens	[1]
	Bifunctional epoxide hydrolase 2 (EPHX2)	DME Info	Homo sapiens	[2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data	Bifunctional epoxide hydrolase 2 (EPHX2)	DME Info	IC50 = 2.2 microM	[2]

References
1	Molecular actions of ebselen--an antiinflammatory antioxidant. Gen Pharmacol. 1995 Oct;26(6):1153-69.
2	Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorg Med Chem Lett. 2013 Jul 1;23(13):3818-21.

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