General Information of Xenobiotics (ID: XEO00585)
Xenobiotics Name
Tetrahydropalmatine
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 2 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
5417
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Galactose kinase (GALK1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Gamma-Glu-X carboxypeptidase (GGH) DME Info Homo sapiens [2]
References
1 Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells. Toxicol Appl Pharmacol. 2009 Nov 1;240(3):355-66.
2 Estrogen-responsive genes newly found to be modified by TCDD exposure in human cell lines and mouse systems. Mol Cell Endocrinol. 2007 Jun 30;272(1-2):38-49.

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