General Information of Xenobiotics (ID: XEO00607)
Xenobiotics Name
Liarozole
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 2 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
60652
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Retinoic acid 4-hydroxylase 26A1 (CYP26A1) DME Info Homo sapiens [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Retinoic acid 4-hydroxylase 26A1 (CYP26A1) DME Info IC50 = 0.54 microM [1]
References
1 Synthesis and biological evaluation of 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propyl derivatives as small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26). J Med Chem. 2011 Oct 13;54(19):6803-11.

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