Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00639)
Xenobiotics Name
URB-597
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 1 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
1383884
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Carboxylesterase 1 (CES1) DME Info Homo sapiens [1]
Carboxylesterase 2 (CES2) DME Info Homo sapiens [1]
Oleamide hydrolase 1 (FAAH) DME Info Homo sapiens [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Oleamide hydrolase 1 (FAAH) DME Info IC50 = 0.00024 microM [2]
References
1 Parabens inhibit fatty acid amide hydrolase: a potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. Toxicol Lett. 2016 Nov 16;262:92-99.
2 Piperidinyl thiazole isoxazolines: a new series of highly potent, slowly reversible FAAH inhibitors with analgesic properties. Bioorg Med Chem Lett. 2016 Jun 15;26(12):2965-2973.

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