Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00643)
Xenobiotics Name
Leukotriene B4
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 2 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
5280492
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Corticosteroid 11-beta-dehydrogenase 2 (HSD11B2) DME Info Homo sapiens [1], [2]
References
1 Prostaglandins and leukotriene B4 are potent inhibitors of 11beta-hydroxysteroid dehydrogenase type 2 activity in human choriocarcinoma JEG-3 cells. Biol Reprod. 1999 Jul;61(1):40-5.
2 Effect of the interaction between lipoxygenase pathway and progesterone on the regulation of hydroxysteroid 11-Beta dehydrogenase 2 in cultured human term placental trophoblasts. Biol Reprod. 2008 Mar;78(3):514-20.

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