General Information of Xenobiotics (ID: XEO00652)
Xenobiotics Name
Seocalcitol
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 3 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
5288149
DME(s) Modulated by This Xenobiotics
DME(s) Induced by This Xenobiotics
Aldo-keto reductase 1C1 (AKR1C1) DME Info Homo sapiens [1]
Aldo-keto reductase 1C3 (AKR1C3) DME Info Homo sapiens [2], [3]
Arachidonate 5-lipoxygenase (ALOX5) DME Info Homo sapiens [4]
Carbonic anhydrase II (CA2) DME Info Homo sapiens [4]
Vitamin D(3) 24-hydroxylase (CYP24A1) DME Info Homo sapiens [4]
Cytochrome P450 3A7 (CYP3A7) DME Info Homo sapiens [4]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [4]
Thioredoxin reductase TR1 (TXNRD1) DME Info Homo sapiens [4]
References
1 High selenium status in individuals exposed to arsenic through coal-burning in Shaanxi (PR of China) modulates antioxidant enzymes, heme oxygenase-1 and DNA damage. Clin Chim Acta. 2010 Sep 6;411(17-18):1312-8.
2 Selenium increases expression of HSP70 and antioxidant enzymes to lessen oxidative damage in Fincoal-type fluorosis. J Toxicol Sci. 2009 Oct;34(4):399-405.
3 Selenium deficiency alters epithelial cell morphology and responses to influenza. Free Radic Biol Med. 2007 Jun 15;42(12):1826-37.
4 Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer. J Natl Cancer Inst. 2009 Mar 4;101(5):306-20.

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