Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00660)
Xenobiotics Name
7-hydroxymethotrexate
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 1 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
5484402
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Folylpolyglutamate synthase (FPGS) DME Info Homo sapiens [1]
References
1 Gene expression profiling of leukemia T-cells resistant to methotrexate and 7-hydroxymethotrexate reveals alterations that preserve intracellular levels of folate and nucleotide biosynthesis. Biochem Pharmacol. 2009 Apr 15;77(8):1410-7.

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