General Information of Xenobiotics (ID: XEO00672)
Xenobiotics Name
TOK-001
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 2 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
11188409
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Steroid 17-alpha-monooxygenase (CYP17A1) DME Info Homo sapiens [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Steroid 17-alpha-monooxygenase (CYP17A1) DME Info IC50 = 0.3 microM [1]
References
1 Discovery and development of Galeterone (TOK-001 or VN/124-1) for the treatment of all stages of prostate cancer. J Med Chem. 2015 Mar 12;58(5):2077-87.

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