Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00673)
Xenobiotics Name
ZIO-101
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 2 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
11683005
DME(s) Modulated by This Xenobiotics
DME(s) Induced by This Xenobiotics
Quinone reductase 1 (NQO1) DME Info Homo sapiens [1]
Thioredoxin reductase TR1 (TXNRD1) DME Info Homo sapiens [1]
Uridine phosphorylase 1 (UPP1) DME Info Homo sapiens [2]
References
1 The novel arsenical Darinaparsin circumvents BRG1-dependent, HO-1-mediated cytoprotection in leukemic cells. Leukemia. 2013 Nov;27(11):2220-8.
2 Darinaparsin: solid tumor hypoxic cytotoxin and radiosensitizer. Clin Cancer Res. 2012 Jun 15;18(12):3366-76.

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