General Information of Xenobiotics (ID: XEO00689)
Xenobiotics Name
AA-861
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Preclinical/Patented Drug
Structure
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3D MOL 2D MOL
PubChem CID
1967
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Arachidonate 5-lipoxygenase (ALOX5) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Corticosteroid 11-beta-dehydrogenase 2 (HSD11B2) DME Info Homo sapiens [2]
References
1 Species difference of 5-lipoxygenase derived from polymorphonuclear leukocytes on sensitivity to drugs. Jpn J Pharmacol. 1989 May;50(1):37-46.
2 Effect of the interaction between lipoxygenase pathway and progesterone on the regulation of hydroxysteroid 11-Beta dehydrogenase 2 in cultured human term placental trophoblasts. Biol Reprod. 2008 Mar;78(3):514-20.

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