Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00697)
Xenobiotics Name
Tetramethylpyrazine
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Preclinical/Patented Drug
Structure
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3D MOL 2D MOL
PubChem CID
14296
DME(s) Modulated by This Xenobiotics
DME(s) Induced by This Xenobiotics
Catalase (CAT) DME Info Homo sapiens [1]
Steroid 11-beta-hydroxylase (CYP11B1) DME Info Homo sapiens [1], [2]
References
1 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated production of reactive oxygen species is an essential step in the mechanism of action to accelerate human keratinocyte differentiation. Toxicol Sci. 2013 Mar;132(1):235-49.
2 Differentiation-specific factors modulate epidermal CYP1-4 gene expression in human skin in response to retinoic acid and classic aryl hydrocarbon receptor ligands. J Pharmacol Exp Ther. 2006 Dec;319(3):1162-71.

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