General Information of Xenobiotics (ID: XEO00766)
Xenobiotics Name
1,10-phenanthroline
Xenobiotics Type
Other Chemical Compound(s) or Element(s)
Classification
Chemical Compound
Structure
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3D MOL 2D MOL
PubChem CID
1318
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aldo-keto reductase 1C1 (AKR1C1) DME Info Homo sapiens [1], [2]
Aldo-keto reductase 1C2 (AKR1C2) DME Info Homo sapiens [2]
Aldo-keto reductase 1C3 (AKR1C3) DME Info Homo sapiens [2]
Aldo-keto reductase 1C4 (AKR1C4) DME Info Homo sapiens [2]
Alanyl aminopeptidase (ANPEP) DME Info Homo sapiens [3]
Catalase (CAT) DME Info Homo sapiens [4]
References
1 Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells. Biochem J. 1996 Jan 15;313 ( Pt 2)(Pt 2):373-6.
2 Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone. Chem Biol Interact. 2003 Feb 1;143-144:503-13.
3 Synergistic inhibition of the enzymatic activity of aminopeptidase N by divalent metal ion chelators. Fundam Clin Pharmacol. 2006 Dec;20(6):613-9.
4 Identification of chemical compounds that induce HIF-1alpha activity. Toxicol Sci. 2009 Nov;112(1):153-63.

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