General Information of Xenobiotics (ID: XEO00832)
Xenobiotics Name
Calcium
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
5460341
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Sodium/potassium-transporting ATPase gamma (FXYD2) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Nitric oxide synthase endothelial (NOS3) DME Info Homo sapiens [2]
Serum paraoxonase/arylesterase 1 (PON1) DME Info Homo sapiens [3]
Transglutaminase K (TGM1) DME Info Homo sapiens [4]
References
1 Heterologous expression of the Na(+),K(+)-ATPase gamma subunit in Xenopus oocytes induces an endogenous, voltage-gated large diameter pore. J Physiol. 2001 Sep 1;535(Pt 2):407-17.
2 Arsenite promotes apoptosis and dysfunction in microvascular endothelial cells via an alteration of intracellular calcium homeostasis. Toxicol In Vitro. 2012 Apr;26(3):386-95.
3 Esterase detoxication of acetylcholinesterase inhibitors using human liver samples in vitro. Toxicology. 2016 Apr 15;353-354:11-20.
4 Effects of a calcium receptor activator on the cellular response to calcium in human keratinocytes. J Invest Dermatol. 1999 Sep;113(3):340-5.

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