General Information of Xenobiotics (ID: XEO00904)
Xenobiotics Name
Pentabromophenol
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Acute Toxic Substance
Structure
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3D MOL 2D MOL
PubChem CID
11852
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
HMG-CoA reductase (HMGCR) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cholesterol desmolase (CYP11A1) DME Info Homo sapiens [2]
Steroid 17-alpha-monooxygenase (CYP17A1) DME Info Homo sapiens [2]
Steroid 21-hydroxylase (CYP21A2) DME Info Homo sapiens [2]
Estradiol 17-beta-dehydrogenase 1 (HSD17B1) DME Info Homo sapiens [1]
Beta-HSD adrenal and gonadal type (HSD3B2) DME Info Homo sapiens [3]
References
1 Transcriptional profiling of human bronchial epithelial cell BEAS-2B exposed to diesel and biomass ultrafine particles. BMC Genomics. 2018 Apr 27;19(1):302.
2 Global gene expression profiling of human bronchial epithelial cells exposed to airborne fine particulate matter collected from Wuhan, China. Toxicol Lett. 2014 Jul 3;228(1):25-33.
3 Transcriptome analysis of airborne PM2.5-induced detrimental effects on human keratinocytes. Toxicol Lett. 2017 May 5;273:26-35.

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