Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00939)
Xenobiotics Name
Benomyl
Xenobiotics Type
Fungicide(s), Herbicide(s) or Insecticide(s)
Classification
Fungicide
Structure
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3D MOL 2D MOL
PubChem CID
28780
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Steroid 17-alpha-monooxygenase (CYP17A1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Aromatase (CYP19A1) DME Info Homo sapiens [2]
References
1 Antiandrogenic mechanisms of pesticides in human LNCaP prostate and H295R adrenocortical carcinoma cells. Toxicol Sci. 2015 Jan;143(1):126-35.
2 A benzimidazole fungicide, benomyl, and its metabolite, carbendazim, induce aromatase activity in a human ovarian granulose-like tumor cell line (KGN). Endocrinology. 2004 Apr;145(4):1860-9.

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