General Information of Xenobiotics (ID: XEO01025)
Xenobiotics Name
Styrene
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Health Hazard/Toxicant
Structure
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3D MOL 2D MOL
PubChem CID
7501
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Porphobilinogen synthase (ALAD) DME Info Homo sapiens [1]
Catalase (CAT) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [3]
References
1 Treatment of lung cancer cells with cytotoxic levels of sodium selenite: effects on the thioredoxin system. Biochem Pharmacol. 2008 Jun 1;75(11):2092-9.
2 Distinct effects of different concentrations of sodium selenite on apoptosis, cell cycle, and gene expression profile in acute promyeloytic leukemia-derived NB4 cells. Ann Hematol. 2006 Jul;85(7):434-42.
3 Mitochondrial thioredoxin reductase inhibition, selenium status, and Nrf-2 activation are determinant factors modulating the toxicity of mercury compounds. Free Radic Biol Med. 2014 Aug;73:95-105.

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