Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01096)
Xenobiotics Name
15d-PGJ2
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Investigative Agent
Structure
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3D MOL 2D MOL
PubChem CID
5311211
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Lauric acid omega-hydroxylase (CYP4A11) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [2]
References
1 CYP4A11 is repressed by retinoic acid in human liver cells. FEBS Lett. 2006 Jun 12;580(14):3361-7.
2 The PPARgamma ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation of human glioblastoma cell lines. Int J Oncol. 2004 Aug;25(2):493-502.

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