Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01098)
Xenobiotics Name
18alpha-glycyrrhetinic acid
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=73398"></iframe>
3D MOL 2D MOL
PubChem CID
73398
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) DME Info Homo sapiens [1]
Corticosteroid 11-beta-dehydrogenase 2 (HSD11B2) DME Info Homo sapiens [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) DME Info IC50 = 0.0086 microM [1]
Corticosteroid 11-beta-dehydrogenase 2 (HSD11B2) DME Info IC50 = 0.0012 microM [2]
References
1 Potent and novel 11beta-HSD1 inhibitors identified from shape and docking based virtual screening. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5739-44.
2 Hupehenols A-E, selective 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors from Viburnum hupehense. J Nat Prod. 2015 Feb 27;78(2):330-4.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.