Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01123)
Xenobiotics Name
GW9662
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Investigative Agent
Structure
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3D MOL 2D MOL
PubChem CID
644213
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Vitamin D(3) 25-hydroxylase (CYP27A1) DME Info Homo sapiens [1]
Cytochrome P450 4F2 (CYP4F2) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Quinone reductase 1 (NQO1) DME Info Homo sapiens [3]
References
1 Resveratrol mediates anti-atherogenic effects on cholesterol flux in human macrophages and endothelium via PPARgama and adenosine. Eur J Pharmacol. 2013 Jan 5;698(1-3):299-309.
2 CYP4F2 repression and a modified alpha-tocopherol (vitamin E) metabolism are two independent consequences of ethanol toxicity in human hepatocytes. Toxicol In Vitro. 2017 Apr;40:124-133.
3 Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening. J Biol Chem. 2012 Sep 21;287(39):33001-13.

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