General Information of Xenobiotics (ID: XEO01246)
Xenobiotics Name
Chlorogenic acid
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 2 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
1794427
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Monoamine oxidase type A (MAO-A) DME Info Homo sapiens [1]
Monoamine oxidase type B (MAO-B) DME Info Homo sapiens [1]
Steroid 5-alpha-reductase 2 (SRD5A2) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Nitric oxide synthase endothelial (NOS3) DME Info Homo sapiens [2]
Quinone reductase 1 (NQO1) DME Info Homo sapiens [3]
References
1 Combining initro and in silico approaches to evaluate the multifunctional profile of rosmarinic acid from Blechnum brasiliense on targets related to neurodegeneration. Chem Biol Interact. 2016 Jul 25;254:135-45.
2 Examining the genomic influence of skin antioxidants in vitro. Mediators Inflamm. 2010;2010.
3 Natural polyphenol chlorogenic acid protects against acetaminophen-induced hepatotoxicity by activating ERK/Nrf2 antioxidative pathway. Toxicol Sci. 2018 Mar 1;162(1):99-112.

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