Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01267)
Xenobiotics Name
Cyclic AMP
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 1 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
6076
DME(s) Modulated by This Xenobiotics
DME(s) Induced by This Xenobiotics
Cholesterol desmolase (CYP11A1) DME Info Homo sapiens [1]
Steroid 11-beta-hydroxylase (CYP11B1) DME Info Homo sapiens [2]
Aromatase (CYP19A1) DME Info Homo sapiens [1]
Beta-HSD adrenal and gonadal type (HSD3B2) DME Info Homo sapiens [3]
References
1 Low-dose bisphenol A activates the ERK signaling pathway and attenuates steroidogenic gene expression in human placental cells. Biol Reprod. 2018 Feb 1;98(2):250-258.
2 Flavonoids exhibit diverse effects on CYP11B1 expression and cortisol synthesis. Toxicol Appl Pharmacol. 2012 Feb 1;258(3):343-50.
3 Inhibitory effects of cholesterol sulfate on progesterone production in human granulosa-like tumor cell line, KGN. Endocr J. 2008 Jul;55(3):575-81.

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