General Information of Xenobiotics (ID: XEO01318)
Xenobiotics Name
Glycochenodeoxycholic acid
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
12544
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Nitric oxide synthase endothelial (NOS3) DME Info Homo sapiens [1], [2]
References
1 Calcium-dependent nitric oxide production is involved in the cytoprotective properties of n-acetylcysteine in glycochenodeoxycholic acid-induced cell death in hepatocytes. Toxicol Appl Pharmacol. 2010 Jan 15;242(2):165-72.
2 Mitochondrial-driven ubiquinone enhances extracellular calcium-dependent nitric oxide production and reduces glycochenodeoxycholic acid-induced cell death in hepatocytes. Chem Res Toxicol. 2009 Dec;22(12):1984-91.

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