General Information of Xenobiotics (ID: XEO01494)
Xenobiotics Name
Tunicamycin A
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
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3D MOL 2D MOL
PubChem CID
11104835
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Retinal dehydrogenase 2 (ALDH1A2) DME Info Homo sapiens [1]
Succinate-semialdehyde dehydrogenase (ALDH5A1) DME Info Homo sapiens [2]
Carbonic anhydrase II (CA2) DME Info Homo sapiens [1], [2]
Delta(24)-sterol reductase (DHCR24) DME Info Homo sapiens [1]
Gamma-Glu-X carboxypeptidase (GGH) DME Info Homo sapiens [1]
HMG-CoA reductase (HMGCR) DME Info Homo sapiens [1]
Hypoxanthine phosphoribosyltransferase (HPRT1) DME Info Homo sapiens [1]
Methylsterol monooxygenase 1 (MSMO1) DME Info Homo sapiens [1]
Methionine-R-sulfoxide reductase B2 (MSRB2) DME Info Homo sapiens [1]
Propionyl-CoA carboxylase beta (PCCB) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Asparagine synthetase (ASNS) DME Info Homo sapiens [1]
Serine sulfhydrase (CBS) DME Info Homo sapiens [1]
L-glutamine amidohydrolase (GLS) DME Info Homo sapiens [1], [2]
Peptide methionine sulfoxide reductase (MSRA) DME Info Homo sapiens [1]
NADH-ubiquinone oxidoreductase 20 kDa (NDUFS7) DME Info Homo sapiens [3]
Uridine phosphorylase 1 (UPP1) DME Info Homo sapiens [1]
References
1 Defensive and adverse energy-related molecular responses precede tris (1, 3-dichloro-2-propyl) phosphate cytotoxicity. J Appl Toxicol. 2016 May;36(5):649-58.
2 Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish. Aquat Toxicol. 2012 Jun 15;114-115:173-81.
3 Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators. Cancer Cell. 2006 Oct;10(4):321-30.

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