Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01537)
Xenobiotics Name
Deguelin
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
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3D MOL 2D MOL
PubChem CID
107935
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Nitric oxide synthase inducible (NOS2) DME Info Homo sapiens [1]
Nitric oxide synthase endothelial (NOS3) DME Info Homo sapiens [2]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [1]
References
1 Deguelin inhibits the migration and invasion of U-2 OS human osteosarcoma cells via the inhibition of matrix metalloproteinase-2/-9 in vitro. Molecules. 2014 Oct 15;19(10):16588-608.
2 Liposomal encapsulation of deguelin: evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis. Cancer Prev Res (Phila). 2009 Apr;2(4):361-9.

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