Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01612)
Xenobiotics Name
2-acetyltributylcitrate
Xenobiotics Type
Other Chemical Compound(s) or Element(s)
Classification
Cosmetic Additive
Structure
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3D MOL 2D MOL
PubChem CID
6505
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Steroid 17-alpha-monooxygenase (CYP17A1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cholesterol desmolase (CYP11A1) DME Info Homo sapiens [1]
Aldosterone synthase (CYP11B2) DME Info Homo sapiens [1]
Steroid 21-hydroxylase (CYP21A2) DME Info Homo sapiens [1]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [2]
Beta-HSD adrenal and gonadal type (HSD3B2) DME Info Homo sapiens [1]
References
1 Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids. Toxicology. 2017 Apr 15;381:51-63.
2 Acetyl tributyl citrate, the most widely used phthalate substitute plasticizer, induces cytochrome p450 3a through steroid and xenobiotic receptor. Toxicol Sci. 2011 Oct;123(2):460-70.

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