General Information of Xenobiotics (ID: XEO01976)
Xenobiotics Name
Allicin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 1 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
65036
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Unclear metabolic mechanism (DME-unclear) DME Info Streptococcus mutans [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [2]
Glutamate racemase (MurI) DME Info Streptococcus mutans [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [2]
References
1 S-aryl-L-cysteine sulphoxides and related organosulphur compounds alter oral biofilm development and AI-2-based cell-cell communication. J Appl Microbiol. 2014 Nov;117(5):1472-86.
2 Effects of allicin on the formation of Pseudomonas aeruginosa biofinm and the production of quorum-sensing controlled virulence factors. Pol J Microbiol. 2013;62(3):243-51.

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