General Information of Xenobiotics (ID: XEO03109)
Xenobiotics Name
Defensin heliomicin
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 monooxygenase 51A (cyp51A) DME Info Aspergillus fumigatus [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Cytochrome P450 monooxygenase 51A (cyp51A) DME Info MIC = 6-12 microM [1], [2]
References
1 Insect immunityIsolation from the lepidopteran Heliothis virescens of a novel insect defensin with potent antifungal activity. J Biol Chem. 1999 Apr 2;274(14):9320-6.
2 Solution structures of the antifungal heliomicin and a selected variant with both antibacterial and antifungal activities. Biochemistry. 2001 Oct 9;40(40):11995-2003.

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