Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03415)
Xenobiotics Name
Furanone C-30
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Investigative Agent
Structure
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3D MOL 2D MOL
PubChem CID
9881496
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Unclear metabolic mechanism (DME-unclear) DME Info Streptococcus mutans [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [2]
Glutamate racemase (MurI) DME Info Streptococcus mutans [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [2]
References
1 Use of the quorum sensing inhibitor furanone C-30 to interfere with biofilm formation by Streptococcus mutans and its luxS mutant strain. Int J Antimicrob Agents. 2012 Jul;40(1):30-5.
2 Effect of quorum quenching lactonase in clinical isolates of Pseudomonas aeruginosa and comparison with quorum sensing inhibitors. Front Microbiol. 2017 Feb 14;8:227.

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