Details of Drug-Metabolizing Enzyme (DME)
| General Information of DME (ID: DME1279) | |||||
|---|---|---|---|---|---|
| DME Name | Unclear metabolic mechanism (DME-unclear), Methanobrevibacter oralis | ||||
| Gene Name | DME-unclear | ||||
| Lineage | Species: Methanobrevibacter oralis (Click to Show/Hide the Complete Species Lineage) | ||||
| Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME | |||||
| Tissue Distribution | Primarily distributed in human gut. | ||||
| Full List of Drug(s) Metabolized by This DME | |||||
|---|---|---|---|---|---|
| Drugs Approved by FDA | Click to Show/Hide the Full List of Drugs: 10 Drugs | ||||
Ampicillin |
Drug Info | Approved | Endocarditis | ICD11: 1B12 | [1] |
Chloramphenicol |
Drug Info | Approved | Conjunctivitis | ICD11: 9A60 | [1] |
Ofloxacin |
Drug Info | Approved | Pneumocystis pneumonia | ICD11: CA40 | [1] |
Tetracycline |
Drug Info | Approved | Spotted fever | ICD11: 1C31 | [1] |
Rifampicin |
Drug Info | Approved | Osteoporosis | ICD11: FB83 | [1] |
Amphotericin B |
Drug Info | Approved | Aspergillosis | ICD11: 1F20 | [1] |
Bacitracin |
Drug Info | Approved | Pyothorax | ICD11: CA44 | [1] |
Gentamicin |
Drug Info | Approved | Acute upper respiratory infection | ICD11: CA07 | [1] |
Streptomycin |
Drug Info | Approved | Infectious endocarditis | ICD11: BB40 | [1] |
Vancomycin |
Drug Info | Approved | Methicillin-resistant staphylococcus infection | ICD11: 1D01 | [1] |
| References | |||||
|---|---|---|---|---|---|
| 1 | The antimicrobial resistance pattern of cultured human methanogens reflects the unique phylogenetic position of archaea. J Antimicrob Chemother. 2011 Sep;66(9):2038-44. | ||||
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